Autoimmunity in autism

Autoimmunity in Autism Spectrum Disorders

CTLA4 Gene Variants in Autoimmunity and Cancer: a Comparative Review

Gene association studies are less appealing in cancer compared to autoimmune diseases. Complexity, heterogeneity, variation in histological types, age at onset, short survival, and acute versus chronic conditions are cancer related factors which are different from an organ specific autoimmune disease, such as Grave’s disease, on which a large body of multicentre data is accumulated. For years t...

Wrong About Measles , Cancer & Autism : A Review of Dan Olmsted ’ s Article “ Weekly Wrap : Measles , Cancer , Autoimmunity , Autism ”

A number of organizations as well as bloggers have arisen over the past several decades claiming that vaccines and/or their ingredients cause a number of disorders, foremost among these is autism. The results of their efforts have been a decline in vaccine coverage and a rise in previously rare childhood diseases, resulting in unnecessary suffering, hospitalizations, long-term disabilities, and...

Streptococcal infection-related autoimmunity and autism: crosstalk in protein functional networks

Autism Spectrum Disorders (ASD) is a group of neurodevelopment dysfunctions causing behavioral abnormalities in social, verbal and non-verbal communication. The precise aetiology of ASD is unknown but it is likely to be the outcome of a combination of genetic, neurological, environmental and immunological factors. Streptococcal infection can induce tick disorders and obsessive compulsive disord...

Folate receptor autoimmunity and cerebral folate deficiency in low-functioning autism with neurological deficits.

Reduced folate transport to the CNS was identified in two autism spectrum disorders, i.e., Rett syndrome and infantile low-functioning autism with neurological abnormalities. Twenty-five patients with early-onset low-functioning autism with or without neurological deficits, were evaluated for serum folate, cerebrospinal fluid (CSF) 5-methyltetrahydrofolate (5MTHF), and serum FR autoantibodies o...